Fig. 2

Overexpression of lncRNA-KAT7 inhibited the proliferation, colony formation of HCT116 and DLD1 cells. a HCT116 cells were stably transfected with lncRNA-KAT7 expression plasmid, and the efficiency of lncRNA-KAT7 overexpression was verified by real-time PCR, with the fold change of nearly 90 times. b DLD1 cells were stably transfected with lncRNA-KAT7 expression plasmid, and the efficiency of lncRNA-KAT7 overexpression was verified by real-time PCR, with the fold change of nearly 50 times. c CCK-8 assay showed that the proliferation rate of lncRNA-KAT7 overexpressed HCT116 cells was reduced. d CCK-8 assay showed that the proliferation rate of lncRNA-KAT7 overexpressed DLD1 cells was reduced. e Colony formation assay showed that overexpression of lncRNA-KAT7 reduced the colony formation of HCT116 and DLD1 cells. f EdU assay showed that the proliferation rate of lncRNA-KAT7 overexpressed HCT116 cells was reduced. *P < 0.05, **P < 0.01, ***P < 0.001