Table 1 DNA methylation-driven genes in ESCC
Gene | Normal mean | Tumor mean | logFC | p value | cor |
|---|---|---|---|---|---|
ZNF608 | 0.380014 | 0.513389 | 0.433998 | 0.004147 | − 0.50173 |
ZNF69 | 0.083813 | 0.247231 | 1.560619 | 0.004834 | − 0.50458 |
RGN | 0.495263 | 0.728198 | 0.556136 | 0.005214 | − 0.38076 |
KCNS1 | 0.30212 | 0.424639 | 0.491118 | 0.005214 | − 0.45073 |
HNF1A | 0.28917 | 0.418797 | 0.534334 | 0.005621 | − 0.37047 |
DNALI1 | 0.245787 | 0.362701 | 0.561374 | 0.005621 | − 0.49921 |
PHYHD1 | 0.492102 | 0.614435 | 0.320303 | 0.006056 | − 0.56 |
ZNF790 | 0.065159 | 0.200691 | 1.622936 | 0.006056 | − 0.40059 |
MCHR1 | 0.353121 | 0.48139 | 0.447046 | 0.006056 | − 0.41517 |
G0S2 | 0.171841 | 0.35132 | 1.031706 | 0.007019 | − 0.39798 |
SLC5A10 | 0.582992 | 0.682592 | 0.227548 | 0.007019 | − 0.51545 |
AKR1B10 | 0.556426 | 0.463528 | − 0.26353 | 0.007551 | − 0.65002 |
ABCD1 | 0.536443 | 0.362675 | − 0.56475 | 0.009368 | − 0.53146 |
HCAR1 | 0.364581 | 0.614652 | 0.753531 | 0.011565 | − 0.67757 |
CCDC8 | 0.31382 | 0.494431 | 0.655831 | 0.011565 | − 0.4821 |
CD302 | 0.219885 | 0.267934 | 0.285128 | 0.012393 | − 0.36856 |
MAEL | 0.802284 | 0.705181 | − 0.18612 | 0.012393 | − 0.37241 |
DAPP1 | 0.484881 | 0.36362 | − 0.4152 | 0.015201 | − 0.40053 |
ZKSCAN7 | 0.207497 | 0.321143 | 0.630125 | 0.016254 | − 0.51596 |
FBXO17 | 0.084149 | 0.138557 | 0.719469 | 0.01737 | − 0.49376 |
SELENBP1 | 0.334825 | 0.459392 | 0.456318 | 0.017371 | − 0.39778 |
SPIN3 | 0.461477 | 0.282616 | − 0.70742 | 0.021134 | − 0.38108 |
ZFP36L2 | 0.052163 | 0.158787 | 1.605994 | 0.022539 | − 0.37007 |
IFITM2 | 0.150144 | 0.215658 | 0.522395 | 0.027245 | − 0.45481 |
AHR | 0.607399 | 0.752003 | 0.308094 | 0.027246 | − 0.41065 |
ELF5 | 0.48324 | 0.597947 | 0.307279 | 0.044136 | − 0.50424 |