Fig. 5

Lnc-NORAD knockdown reduced tumor growth in nude mice. a The MDA-MB231 cells were transfected with si-NORAD or si-nc and injected into nude mice. Tumor tissues were harvested and photographed 5 weeks later. b Relative lnc-NORAD expression was detected by RT-PCR in tumor tissues. The relative lnc-NORAD expression of tumors from the MDA-MB-231 cells transfected with si-NORAD or si-nc. c Time-course comparison of tumor growth from the MDA-MB-231 cells. Tumor sizes were measured once a week over 5 weeks and the tumor volume was calculated by L × S/2. d Comparison of tumors weight derived from the MDA-MB-231 cells, which were transfected with si-NORAD or si-nc and injected into nude mice. **p < 0.01 vs the control