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Fig. 3 | Cancer Cell International

Fig. 3

From: LncRNA BCAR4, targeting to miR-665/STAT3 signaling, maintains cancer stem cells stemness and promotes tumorigenicity in colorectal cancer

Fig. 3

BCAR4 facilitated ALDH positive cells viability, migration and self-renewal in CRC. a CCK8, migration and tumorsphere formation assay revealed that ALDH+ CRC cells occupied enhanced capacity of proliferation, migration and self-renewal. b, c CCK8, migration and tumorsphere formation assay revealed the alteration of capacity of proliferation, migration and self-renewal in colon cancer cells with defected BCAR4 function. d q-PCR showed the expression of CSCs markers in ALDH+ or ALDH− HCT8 cells after BCAR4 inhibition. e, f Western blot showed the expression of CSC markers n ALDH+ or ALDH− HCT8 cells after BCAR4 inhibition

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Cancer Cell International

ISSN: 1475-2867

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