MiR-591 functions as tumor suppressor in breast cancer by targeting TCF4 and inhibits Hippo-YAP/TAZ signaling pathway

Table 1 The association of clinicopathological factors with miR-591 expression in 78 breast cancer patients

Characteristics	Total	MiR-591 expression level		P-value
Characteristics	Total	Lower (n = 38)	Higher (n = 40)	P-value
Age (years)				0.267
≤ 45	32	18	14
> 45	46	20	26
Tumor size (cm)				0.519
< 2	30	16	14
> 2	48	22	26
PR status				0.223
No	30	12	18
Yes	48	26	22
TNM stage				0.011*
I/II	50	19	31
III	28	19	9
Lymph node metastasis				0.005*
No	53	20	33
Yes	25	18	7
Bone metastasis				0.615
No	70	34	36
Yes	8	4	4
ER				0.972
No	45	22	23
Yes	33	16	17
Histological grade				0.262
G1/2	52	23	29
G3	26	15	11

ISSN: 1475-2867