Fig. 6
From: Tre2 (USP6NL) promotes colorectal cancer cell proliferation via Wnt/β-catenin pathway
Knockdown of USP6NL inhibited tumorigenicity of HCT116 cells in a Xenograft model. Nude mice were subcutaneously injected with siNC/siUSP6NL transfected HCT116 cells (7 × 107 cells, 100 μl) (n = 6 in each group). a Tumor formation of mice and tumor volume (mm3) from 12th day to 33th day; b tumor weight (g) on 33th day; c apoptosis analysis in tumor using TUNEL technology (×200; d protein levels of USP6NL, β-catenin, Cyclin D1, C-myc and P27 in tumors; **P < 0.01 vs. siNC