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Fig. 8 | Cancer Cell International

Fig. 8

From: Apatinib preferentially inhibits PC9 gefitinib-resistant cancer cells by inducing cell cycle arrest and inhibiting VEGFR signaling pathway

Fig. 8

Apatinib inhibits the tumor growth of PC9GR cell xenograft in mice. a, b Volume changes of tumors in mice bearing PC9GR and PC9 cells, respectively over 21 days by administration of 100 mg/kg apatinib daily. c Tumor weight changes in mice bearing PC9GR or PC9 cells after treatment where PC9GR tumors shrunk the most. d Photographs of mice in each group and e photographs of tumors in each group. Each group has 6 mice or tumors. Each value represents a group mean ± standard deviation. *p < 0.05, **p < 0.01, ***p < 0.001 compared with the control group using the t test

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Cancer Cell International

ISSN: 1475-2867

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