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Table 2 Correlation of miR-137 and GREM1 with clinicopathological features of cervical cancer

From: Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1

Clinicopathological features

n

miR-137 expression

p

GREM1 mRNA expression

p

Age (years)

 ≤ 40

57

0.332 ± 0.066

0.798

1.984 ± 0.195

0.860

 > 40

52

0.329 ± 0.055

 

1.978 ± 0.156

 

Stage

 < II stage

57

0.347 ± 0.064

0.002

1.938 ± 0.174

0.008

 ≥ II stage

52

0.312 ± 0.052

 

2.028 ± 0.170

 

Lymph node metastasis

 No

72

0.341 ± 0.065

0.011

1.951 ± 0.165

0.012

 Yes

37

0.310 ± 0.046

 

2.040 ± 0.187

 

Vascular infiltration

 No

65

0.346 ± 0.070

0.001

1.950 ± 0.199

0.025

 Yes

44

0.307 ± 0.032

 

2.027 ± 0.128

 

Differentiation degree

 Poorly differentiated

31

0.302 ± 0.062

< 0.001

2.084 ± 0.191

< 0.001

 Moderately differentiated

43

0.326 ± 0.061

 

1.994 ± 0.174

 

 Well-differentiated

35

0.361 ± 0.043

 

1.874 ± 0.090

 

Tumor size (cm)

 ≤ 4

60

0.349 ± 0.063

< 0.001

1.928 ± 0.163

< 0.001

 > 4

49

0.308 ± 0.049

 

2.046 ± 0.174

 
  1. Statistical data were presented as mean ± standard deviation; data between two groups were analyzed by paired t-test and comparisons among multiple groups were analyzed by one-way analysis of variance
  2. miR-137 microRNA-137, GREM1 gremlin-1
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Cancer Cell International

ISSN: 1475-2867

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