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Table 2 Correlation of miR-137 and GREM1 with clinicopathological features of cervical cancer

From: Overexpression of mircoRNA-137 inhibits cervical cancer cell invasion, migration and epithelial–mesenchymal transition by suppressing the TGF-β/smad pathway via binding to GREM1

Clinicopathological features n miR-137 expression p GREM1 mRNA expression p
Age (years)
 ≤ 40 57 0.332 ± 0.066 0.798 1.984 ± 0.195 0.860
 > 40 52 0.329 ± 0.055   1.978 ± 0.156  
Stage
 < II stage 57 0.347 ± 0.064 0.002 1.938 ± 0.174 0.008
 ≥ II stage 52 0.312 ± 0.052   2.028 ± 0.170  
Lymph node metastasis
 No 72 0.341 ± 0.065 0.011 1.951 ± 0.165 0.012
 Yes 37 0.310 ± 0.046   2.040 ± 0.187  
Vascular infiltration
 No 65 0.346 ± 0.070 0.001 1.950 ± 0.199 0.025
 Yes 44 0.307 ± 0.032   2.027 ± 0.128  
Differentiation degree
 Poorly differentiated 31 0.302 ± 0.062 < 0.001 2.084 ± 0.191 < 0.001
 Moderately differentiated 43 0.326 ± 0.061   1.994 ± 0.174  
 Well-differentiated 35 0.361 ± 0.043   1.874 ± 0.090  
Tumor size (cm)
 ≤ 4 60 0.349 ± 0.063 < 0.001 1.928 ± 0.163 < 0.001
 > 4 49 0.308 ± 0.049   2.046 ± 0.174  
  1. Statistical data were presented as mean ± standard deviation; data between two groups were analyzed by paired t-test and comparisons among multiple groups were analyzed by one-way analysis of variance
  2. miR-137 microRNA-137, GREM1 gremlin-1