Table 3 Associations between PD-L1 and clinical factors in cervical cancer
From: Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer
Clinical factors | No. of studies | Effects model | OR (95% CI) | p | Heterogeneity I2 (%) Ph | Begg’s p | Egger’s p | |
|---|---|---|---|---|---|---|---|---|
Lymph node metastasis (yes vs no) | 7 | Random | 1.15 (0.59–2.25) | 0.682 | 63.6 | 0.011 | 0.368 | 0.543 |
Tumor size (mm) (≥ 40 vs < 40) | 6 | Random | 1.48 (0.71–3.08) | 0.294 | 67.5 | 0.009 | 0.707 | 0.93 |
FIGO stage (II vs I) | 6 | Fixed | 1.18 (0.83–1.68) | 0.345 | 39.9 | 0.139 | 0.707 | 0.85 |
Depth of invasion (mm) (≥ 10 vs < 10) | 5 | Random | 0.85 (0.4–1.82) | 0.674 | 60.6 | 0.038 | 0.221 | 0.062 |
Lymph-vascular invasion (yes vs no) | 5 | Fixed | 0.84 (0.57–1.22) | 0.357 | 11.4 | 0.341 | 1 | 0.758 |
Age (y) (≥ 45 vs < 45) | 3 | Fixed | 1.14 (0.74–1.77) | 0.554 | 22.7 | 0.274 | 0.296 | 0.24 |