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Table 3 Associations between PD-L1 and clinical factors in cervical cancer

From: Elevated PD-L1 expression predicts poor survival outcomes in patients with cervical cancer

Clinical factors No. of studies Effects model OR (95% CI) p Heterogeneity I2 (%) Ph Begg’s p Egger’s p
Lymph node metastasis (yes vs no) 7 Random 1.15 (0.59–2.25) 0.682 63.6 0.011 0.368 0.543
Tumor size (mm) (≥ 40 vs < 40) 6 Random 1.48 (0.71–3.08) 0.294 67.5 0.009 0.707 0.93
FIGO stage (II vs I) 6 Fixed 1.18 (0.83–1.68) 0.345 39.9 0.139 0.707 0.85
Depth of invasion (mm) (≥ 10 vs < 10) 5 Random 0.85 (0.4–1.82) 0.674 60.6 0.038 0.221 0.062
Lymph-vascular invasion (yes vs no) 5 Fixed 0.84 (0.57–1.22) 0.357 11.4 0.341 1 0.758
Age (y) (≥ 45 vs < 45) 3 Fixed 1.14 (0.74–1.77) 0.554 22.7 0.274 0.296 0.24
  1. FIGO, The International Federation of Gynecology and Obstetrics