Table 2 The prognostic value of eIF3i, eIF3k and the combination of eIF3i and eIF3k in LGG (n = 134 in CGGA dataset)
eIF3 subunit | LGG | Astro, IDH-wildtype | All LGG, IDH-mutant | Astro, IDH-mutant | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | Confident interval | P-value | HR | Confident interval | P-value | HR | Confident interval | P-value | HR | Confident interval | P-value | |||||
Low 95% | High 95% | Low 95% | High 95% | Low 95% | High 95% | Low 95% | High 95% | |||||||||
eIF3i | 3.59 | 2.30 | 5.62 | 2.12E−08 | 2.90 | 1.44 | 5.83 | 2.87E−03 | 4.00 | 2.15 | 7.44 | 1.24E−05 | 4.41 | 2.02 | 9.61 | 1.94E−04 |
eIF3k | 2.13 | 1.39 | 3.27 | 5.61E−04 | 1.24 | 0.64 | 2.39 | 5.27E−01 | 2.36 | 1.31 | 4.24 | 4.03E−03 | 1.78 | 0.92 | 3.47 | 8.86E−02 |
eIF3i and eIF3k | 2.22 | 1.65 | 2.98 | 1.44E−07 | 1.82 | 1.14 | 2.91 | 1.16E−02 | 2.34 | 1.56 | 3.52 | 3.80E−05 | 2.12 | 1.33 | 3.36 | 1.51E−03 |