Fig. 6From: Harmine suppresses hyper-activated Ras–MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegansHarmine functions in its native form to suppress the Muv phenotype. BPI of extracts of worms treated with either 0.4% DMSO vehicle (a) or 80 μM harmine (lower panel, b). The chromatogram contains a new peak, m/z 213 (indicated by a red line). The MS spectrum of a higher energy scan is shown (upper rectangle, b) and indicates the existence of harmine, but not metabolites of harmine, inside the worm bodyBack to article page