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Fig. 6 | Cancer Cell International

Fig. 6

From: Harmine suppresses hyper-activated Ras–MAPK pathway by selectively targeting oncogenic mutated Ras/Raf in Caenorhabditis elegans

Fig. 6

Harmine functions in its native form to suppress the Muv phenotype. BPI of extracts of worms treated with either 0.4% DMSO vehicle (a) or 80 μM harmine (lower panel, b). The chromatogram contains a new peak, m/z 213 (indicated by a red line). The MS spectrum of a higher energy scan is shown (upper rectangle, b) and indicates the existence of harmine, but not metabolites of harmine, inside the worm body

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