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Table 4 Efficiency of serum IQGAP3, B7-H4, COX-2, CEA and CA19-9 in the diagnosis of CRC

From: Clinical value of detecting IQGAP3, B7-H4 and cyclooxygenase-2 in the diagnosis and prognostic evaluation of colorectal cancer

Factor

Sensitivity (%)

Specificity (%)

Youden Index

Accuracy (%)

IQGAP3

89.8

58.8

0.486

0.799

B7-H4

88.1

62.4

0.505

0.795

COX-2

79.2

69.4

0.486

0.796

IQGAP3 + B7-H4

92.9

62.5

0.554

0.876

IQGAP3 + COX-2

91.8

56.8

0.486

0.889

B7-H4 + COX-2

90.6

63.5

0.541

0.875

IQGAP3 + B7-H4 + COX-2

94.1

74.5

0.686

0.926

CEA

60.3

71.8

0.321

0.786

CA19-9

50.2

81.2

0.314

0.777

  1. We analyzed the ROC curves of serum IQGAP3, B7-H4, COX-2, CEA and CA19-9 in CRC patients. Sensitivity, specificity, Youden Index and the AUC value
  2. CRC, colorectal cancer; CI, confidence interval