Variable | Number of patients | PFKFB4 expression | p-valuea | |
---|---|---|---|---|
Negative number (%) | Positive number (%) | |||
Total | 200 | 102 (51.0) | 98 (49.0) | |
Age (years) | 0.453 | |||
≤ 50 | 113 | 55 (48.7) | 58 (51.3) | |
> 50 | 87 | 47 (54.0) | 40 (46.0) | |
Menopausal status | 0.837 | |||
Premenopausal | 121 | 61 (50.4) | 60 (49.6) | |
Postmenopausal | 79 | 41 (51.9) | 38 (48.1) | |
Tumor size (cm) | 0.168 | |||
≤ 2 | 95 | 50 (52.6) | 45 (47.4) | |
> 2, ≤ 5 | 91 | 48 (52.7) | 43 (47.3) | |
> 5 | 8 | 1 (12.5) | 7 (87.5) | |
Cannot be measured | 6 | 3 (50.0) | 3 (50.0) | |
Lymph node status | 0.890 | |||
Negative | 99 | 50 (50.5) | 49 (49.5) | |
Positive | 101 | 52 (51.5) | 49 (48.5) | |
Grade | 0.716 | |||
Grade 1 | 2 | 1 (50.0) | 1 (50.0) | |
Grade 2 | 94 | 52 (55.3) | 42 (44.7) | |
Grade 3 | 56 | 26 (46.4) | 30 (53.6) | |
Unknown | 48 | 23 (47.9) | 25 (52.1) | |
ER status | 0.021 | |||
Negative | 112 | 49 (43.8) | 63 (56.3) | |
Positive | 88 | 53 (60.2) | 35 (39.8) | |
PR status | 0.059 | |||
Negative | 113 | 51 (45.1) | 62 (54.9) | |
Positive | 87 | 51 (58.6) | 36 (41.4) | |
HER2 status | 0.120 | |||
Negative | 99 | 45 (45.5) | 54 (54.5) | |
Positive | 101 | 57 (56.4) | 44 (43.6) | |
Subtypeb | 0.068 | |||
Luminal | 100 | 58 (58.0) | 42 (42.0) | |
HER2-enriched | 50 | 25 (50.0) | 25 (50.0) | |
Triple-negative | 50 | 19 (38.0) | 31 (62.0) |