Fig. 9

Knockdown of MMP7 with specific siRNA could reverse DKK1 knockdown-induced the cell invasion in MCF-7 and MDA-MB-231 cells. a Western blot assay suggested MMP7 siRNA could attenuate the protein expression of MMP7 in MCF-7 and MDA-MB-231 cells treated with DKK1 shRNA. Results are presented as mean ± SEM, ***p < 0.001, n = 5 per group, Student's test was used. b Transwell chamber coated with Matrigel assay showed MMP7 siRNA could reverse DKK1 knockdown-induced the cell invasion in MCF-7 and MDA-MB-231 cells. Results are presented as mean ± SEM, ***p < 0.001, n = 5 per group, Student's test was used