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Table 1 Functional and pathway enrichment analysis of the DEGs in module

From: Identification of potential key genes and pathways predicting pathogenesis and prognosis for triple-negative breast cancer

Category

Term

Description

Count

P-value

BP term

GO:0007018

Microtubule-based movement

6

9.15E−07

BP term

GO:0000070

Mitotic sister chromatid segregation

4

1.81E−05

BP term

GO:0007080

Mitotic metaphase plate congression

4

5.69E−05

BP term

GO:0051301

Cell division

4

3.19E−04

BP term

GO:0000281

Mitotic cytokinesis

3

0.001

CC term

GO:0030496

Midbody

6

2.73E−06

CC term

GO:0005871

Kinesin complex

5

8.61E−06

CC term

GO:0051233

Spindle midzone

4

1.11E−05

CC term

GO:0000942

Condensed nuclear chromosome outer kinetochore

3

2.29E−05

CC term

GO:0000776

Kinetochore

4

4.57E−04

MF term

GO:0005524

ATP binding

14

4.19E−07

MF term

GO:0003777

Microtubule motor activity

5

9.01E−06

MF term

GO:0016887

ATPase activity

4

0.001

MF term

GO:0003697

Single-stranded DNA binding

3

0.006

MF term

GO:0003688

DNA replication origin binding

2

0.020

KEGG pathway

cfa04110

Cell cycle

8

4.13E−10

KEGG pathway

cfa04914

Progesterone-mediated oocyte maturation

4

4.04E−04

KEGG pathway

cfa04114

Oocyte meiosis

4

7.89E−04

  1. BP: Biological process; CC: cellular component; DEGs: differentially expressed genes; GO: Gene Ontology; KEGG: Kyoto Encyclopedia of Genes and Genomes; MF: molecular function