Cancer Cell International

Table 1 Univariate and multivariate analysis for disease-free survival in total 290 cases

From: LINC00309 is associated with short disease-free survival in breast cancer

	Univariate analysis		Multivariate analysis
	Hazard ratio (95% CI)	p^a value	Hazard ratio (95% CI)	p^a value
Age
> 40 vs. ≤ 40	1.618 (0.828–3.159)	0.159	1.386 (0.695–2.762)	0.354
Tumor size
≤ 2 vs. > 2	1.444 (0.865–2.410)	0.159	1.133 (0.651–1.9718)	0.434
Lymph node status
Negative vs. positive	5.855 (1.045–1.518)	0.016	1.544 (1.102–1.529)	0.002
Vessel invasion
Negative vs. positive	2.311 (1.304–4.097)	0.004	1.779 (0.816–2.924)	0.182
ER status
Negative vs. positive	0.703 (0.396–1.250)	0.230	0.150 (0.023–0.974)	0.057
PR status
Negative vs. positive	0.807 (0.453–1.438)	0.467	5.466 (0.831–35.955)	0.077
Ki-67
Negative vs. positive	1.911 (1.075–3.395)	0.027	1.053 (1.053–3.733)	0.034
HER-2/neu status
Negative vs. positive	0.712 (0.403–1.260)	0.244	0.324 (0.324–1.143)	0.123
LINC00309
Low vs. high	1.990 (1.069–3.703)	0.030	2.127 (1.074–4.212)	0.030

CI confidence interval, HER-2 human epidermal growth factor receptor 2, PR progesterone receptor
^ap is based on the Cox regression test

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