Table 2 Clinicopathological variables and the expression of LINC00309 in HR-positive cases
From: LINC00309 is associated with short disease-free survival in breast cancer
Variables | Number of patients (%) | LINC00309 expression | pa value | |
|---|---|---|---|---|
Low n (%) | High n (%) | |||
Total | 161 | 70 (43.5) | 91 (56.5) | Â |
Age | 0.942 | |||
 ≤ 40 years | 28 (17.4) | 12 (7.5) | 16 (9.9) |  |
 > 40 years | 133 (82.6) | 58 (36.0) | 75 (46.6) |  |
Tumor size | 0.552 | |||
 T1 | 59 (36.6) | 23 (14.3) | 36 (22.4) |  |
 T2 | 96 (59.6) | 45 (28.0) | 51 (31.7) |  |
 T3 | 6 (3.7) | 2 (1.2) | 4 (2.5) |  |
Lymph node status | 0.824 | |||
 pN0 | 69 (42.9) | 31 (19.3) | 38 (23.6) |  |
 pN1 | 45 (28.0) | 19 (11.8) | 26 (16.1) |  |
 pN2 | 21 (13.0) | 9 (5.6) | 12 (7.5) |  |
 pN3 | 25 (15.5) | 10 (6.2) | 15 (9.3) |  |
 Unknown | 1 (0.6) | 1 (0.6) | 0 (0.0) |  |
Vessel invasion | 0.708 | |||
 Negative | 87 (54.0) | 39 (24.2) | 48 (29.8) |  |
 Positive | 74 (46.0) | 31 (19.3) | 43 (26.7) |  |
HER-2/neu status | 0.011 | |||
 Negative | 120 (74.5) | 46 (28.6) | 74 (46.0) |  |
 Positive | 36 (22.4) | 19 (11.8) | 17 (10.6) |  |
 Unknown | 5 (3.1) | 5 (3.1) | 0 (0.0) |  |
Ki-67 status | 0.489 | |||
 Negative | 108 (67.1) | 49 (30.4) | 59 (36.6) |  |
 Positive | 53 (32.9) | 21 (13.0) | 32 (19.9) |  |
Chemotherapy regimes | 0.271 | |||
 CAFb | 30 (18.6) | 15 (9.3) | 15 (9.3) |  |
 TC (± H)c | 11 (6.8) | 2 (1.2) | 9 (5.6) |  |
 CAF-T (± H)d | 85 (52.8) | 39 (24.2) | 46 (28.6) |  |
 Other | 6 (3.7) | 4 (2.5) | 2 (1.2) |  |
 None | 20 (12.4) | 6 (3.7) | 14 (8.7) |  |
 Unknown | 9 (5.6) | 4 (2.5) | 5 (3.1) |  |
Hormone therapy | 0.358 | |||
 SERMs related | 62 (38.5) | 25 (15.5) | 37 (23.0) |  |
 TAM only | 38 (23.6) | 14 (8.7) | 24 (14.9) |  |
 TAM + LHRH | 6 (3.7) | 1 (0.6) | 5 (3.1) |  |
 TAM (major)-AIse | 6 (3.7) | 3 (1.9) | 3 (1.9) |  |
 Othersf | 12 (7.5) | 7 (4.3) | 5 (3.1) |  |
 AIs related | 75 (46.6) | 31 (19.3) | 44 (27.3) |  |
 AIs only | 60 (37.3) | 25 (15.5) | 35 (21.7) |  |
 AIs + LHRH | 3 (1.9) | 1 (0.6) | 2 (1.2) |  |
 TAM-AIs (major)g | 9 (5.6) | 5 (3.1) | 4 (2.5) |  |
 AIs-othersh | 3 (1.9) | 0 (0.0) | 3 (1.9) |  |
 Unknown | 24 (14.9) | 14 (8.7) | 10 (6.2) |  |