Table 2 Summary of lncRNAs with their potential targets and pathways

LET

Downregulated

NA

↓Cell proliferation, invasion and tumor growth; ↑apoptosis; G0/G1 arrest

[10]

LINC00152

Upregulated

miR-138

↑Cell proliferation, migration, invasion and EMT; ↑tumor peritoneal spreading and metastasis; ↓apoptosis; PI3K/AKT pathway; LINC00152/miR-138/HIF-1α pathway

[16, 17]

MEG3

Downregulated

EZH2, LATS2

↓Cell proliferation, invasion, EMT and tumor growth; ↑cell apoptosis; G1/G0 arrest; ↑EZH2 ubiquitination; ↑p53; ↓CDK4 and CyclinD1

[12, 18]

ANRIL

Upregulated

NA

↑Cell proliferation and tumor growth; ↓apoptosis; ↓p53; ↑CyclinD1

[12]

GCASPC

Downregulated

Pyruvate carboxylase

↓Cell proliferation and tumor growth; ↓pyruvate carboxylase

[11]

MALAT1

Upregulated

miR-206

↑Cell proliferation and invasion; ↓cell apoptosis; ↓miR-206; ↑KRAS and annexin a2

[9, 19, 32, 33]

MINCR

Upregulated

miR-26a-5p

↑Cell proliferation, EMT and invasion; ↓cell apoptosis; MINCR/miR-26a-5p/EZH2 axis

[20]

AFAP1-AS1

Upregulated

NA

↑Cell proliferation, EMT and tumor invasion

[21]

UCA1

Upregulated

EZH2

↑Cell proliferation, EMT and metastasis; ↓p21 and E-cadherin

[22]

PAGBC

Upregulated

miR-133b, miR-511

↑Cell proliferation, migration and invasion; ↑tumor growth and metastasis; ↑SOX4 and PIK3R3; AKT/mTOR pathway; PABPC1

[23]

Loc344887

Upregulated

NA

↑Cell proliferation, mobility, EMT and invasion

[24]

ROR

Upregulated

NA

↑Cell proliferation, migration, EMT and invasion

[25]

HEGBC

Upregulated

IL-11

↑Cell proliferation, migration; ↑tumor growth and metastasis; IL-11/STAT3 pathway

[26]

H19

Upregulated

AKT2

↑Cell proliferation and invasion; H19/miR-194-5p/AKT2 axis

[27, 28]

PVT1

Upregulated

miR-143

↑Cell proliferation, migration and invasion; ↑tumor growth; ↑MMP-2 and MMP-9; PVT1/miR-143/HK2 axis

[29]