Caveolin-1 enhances brain metastasis of non-small cell lung cancer, potentially in association with the epithelial-mesenchymal transition marker SNAIL

Table 5 Univariate and multivariate analysis for overall survival predictors in 211 patients with primary NSCLC

Characteristics	No.	Mean survival (months)	P value (univariate)^a	P-value (multivariate)^a	Hazard ratio	95% Confidence index
Age
< 63	84	83.1	0.056	0.109	1	0.935–1.942
≥ 63	127	66.3	0.056	0.109	1.348	0.935–1.942
Sex
Male	165	68.7	0.099	0.162	1	0.456–1.141
Female	46	90.5	0.099	0.162	0.721	0.456–1.141
Histology
SQC	73	78.7	0.280	0.007	1	1.168–2.659
Non-SQC	138	69.9	0.280	0.007	1.762	1.168–2.659
BM
Absent	162	87.7	< 0.001	< 0.001	0.181	0.124–0.264
Present	49	28.3	< 0.001	< 0.001	1	0.124–0.264
Tumor Cav-1
Low	128	73.1	0.260	0.005	1	1.175–2.502
High	83	71.0	0.260	0.005	1.715	1.175–2.502

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