Fig. 3

miR-125b-5p inhibits HCC cell migration and invasion. a miR-125b-5p expression was negatively associated with metastasis according to GSEA of the TCGA cohort (enrichment score = − 0.551; P < 0.001). b HCC cell migration and invasion were evaluated in cells transfected with the miR-125b-5p mimic and using Transwell and Boyden assays. c, d Statistical analysis of Transwell and Boyden assay results (n = 3; Student’s t test). e HCC cell migration and invasion were evaluated in cells transfected with miR-125b-5p inhibitor and using Transwell and Boyden assays. f, g Statistical analysis of Transwell and Boyden assay results (n = 3; Student’s t test). *P < 0.05; **P < 0.01; ***P < 0.001