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Fig. 7 | Cancer Cell International

Fig. 7

From: miR-450b-5p loss mediated KIF26B activation promoted hepatocellular carcinoma progression by activating PI3K/AKT pathway

Fig. 7

Overexpression of KIF26B could reverse tumor suppressive effect of miR-450b-5p in HCC cells. a KIF26B expression under condition of miR-450b-5p mimics, miR-450b-5p mimics and KIF26B or negative control. b Cell viability of Hep-3B and HCC-LM3 cells under treatment of miR-450b-5p mimics, miR-450b-5p mimics and KIF26B and negative control in 24 h, 48 h and 72 h. c, d Cell proliferation rate and invasion ability of Hep-3B and HCC-LM3 cells under treatment of miR-450b-5p mimics, miR-450b-5p mimics and KIF26B and negative control. e Tumor formation ability of HCC cells with miR-450b-5p mimics, miR-450b-5p mimics and KIF26B and negative control was compared in vitro. Mean ± SD, *p < 0.05, unpaired Student’s t test or one-way ANNOVA followed by multiple t test

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