Fig. 1

RASSF-1A gene is down-regulated in tumor tissues of patients with oral squamous cell carcinoma and is associated with patient survival. a, b Detection of RASSF-1A mRNA expression in tumor tissues and paracancerous tissues of patients with oral cancer by qPCR (n = 6 in normal group, n = 7 in OSCC group; *p < 0.05). c, d Kaplan–Meier plots for patients expressing RASSF-1A above (high) and below (low) the first quartile (left panel) and median (right panel) were constructed with Taylor et al. data via the web interface Betastasis. e Western blot analysis of RASSF-1A protein expression in tumor tissues of patients with oral cancer. f Statistical analysis of RASSF-1A protein expression in tumor tissues of patients with oral cancer by western blot (n = 6 in normal group, n = 7 in OSCC group; *p < 0.05)