Cancer Cell International

Table 1 Associations of expression of CDK5 and BIN1 with patient clinical parameters of NSCLC patients

From: CDK5 neutralizes the tumor suppressing effect of BIN1 via mediating phosphorylation of c-MYC at Ser-62 site in NSCLC

	n	Expression of CDK5 (n)		P	Expression of BIN1 (n)		P
	n	High	Low	P	High	Low	P
Gender
Male	103	61	42	0.190	43	60	0.791
Female	50	24	26	0.190	22	28	0.791
Age
≤ 60	109	62	47	0.604	46	63	0.912
> 60	44	23	21	0.604	19	25	0.912
TNM stage
I + II	86	33	53	< 0.001	47	39	0.001
III	67	52	15	< 0.001	18	49	0.001
Invasion range
T1 + T2	59	21	38	< 0.001	32	27	0.020
T3	94	64	30	< 0.001	33	61	0.020
Lymph node metastasis
Negative	75	27	48	< 0.001	43	32	< 0.001
Positive	78	58	20	< 0.001	22	56	< 0.001

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ISSN: 1475-2867

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