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Fig. 4 | Cancer Cell International

Fig. 4

From: Prognostic significance of TOP2A in non-small cell lung cancer revealed by bioinformatic analysis

Fig. 4

Prognosis value and expression analysis of TOP2A. a Expression of TOP2A in different types of human cancers. This graphic generated by Oncomine indicates the numbers of datasets with statistically significant (P < 0.01) mRNA over-expression (red) or down-expression (blue) of TOP2A (cancer vs. normal tissue). The threshold was designed with the following parameters: P-value of 1E−4, fold change of 2, and gene ranking of 10%. b Expression of TOP2A in different types of human cancers by GEPIA analysis. c Overall survival value of TOP2A by Kaplan–Meier survival analysis. d Aberrant gain of expression of TOP2A in NSCLC comparing to normal lung tissues, including lung adenocarcinoma (left column) squamous cancer (right column). *P < 0.05

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