Fig. 1

KLF8 is overexpressed in human lung cancer tissues. a The mRNA level of KLF8 is overexpressed in human lung cancer tissues (n = 34) compared with non-cancer tissues (n = 16). ***p < 0.001. b Western blot results showing KLF8 expression in human lung cancer tissues and non-cancer tissues. c Quantifications of KLF8 protein level analyzed by western blot. N = 6, **p < 0.01. d Representative histochemical staining of KLF8 expression in non-cancer and lung cancer tissues. Bar = 100 μm. e Quantifications of KLF8 expression in non-cancer (n = 5) and lung cancer tissues (n = 5).***p < 0.001. f The mRNA level of KLF8 is overexpressed in human lung cancer cell lines (A549, H1975, H1299, H460, and H520) compared with normal lung epithelial cell line (BEAS-2B). *p < 0.05, **p < 0.01 and ***p < 0.001. n = 3 in each group