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Table 1 Summary of the main characteristics of the studies enrolled in the meta-analysis

From: The prognostic value of long noncoding RNA SNHG16 on clinical outcomes in human cancers: a systematic review and meta-analysis

Study Year Country of origin Tumor type Sample
type
Sample
Size
SNHG16 expression Follow-up months Detection
assay
Clinical
stage
Metastasis analysis Outcome measure Survival analysis Cut-off value Study
design
NOS
High Low
Cao et al. 2017 China Bladder cancer Tissue 46 25 21 60 qRT-PCR N/A LNM/DM OS Univariate Mean Cohort study 8
Duan et al. 2016 China Bladder cancer Serum 59 N/A N/A 80 qRT-PCR N/A LNM RFS Univariate Median Cohort study 9
Han et al. 2018 China Esophageal squamous cell carcinoma Tissue 128 65 63 60 qRT-PCR TNM
I-IV
LNM OS Multivariate Median Cohort study 8
Han et al. 2019 China Non-small cell lung cancer Tissue 66 33 33 60 qRT-PCR TNM
I-IV
LNM OS/DFS Multivariate Median Cohort study 8
Lu et al. 2018 China Glioma Tissue 48 25 23 60 qRT-PCR N/A N/A OS/PFS Multivariate Median Cohort study 8
Yang et al. 2018 China Ovarian cancer Tissue 103 47 56 60 qRT-PCR FIGO
I-IV
DM OS Univariate Mean Cohort study 8
Zhang et al. 2018 China Bladder cancer Serum 74 N/A N/A 76 qRT-PCR N/A LNM RFS Univariate Median Cohort study 9
Zhu et al. 2018 China Cervical cancer Tissue 38 22 16 60 qRT-PCR FIGO
I-III
LNM OS Multivariate Median Cohort study 8
  1. DFS disease-free survival, DM distant metastasis, FIGO the International Federation of Gynecology and Obstetrics, LNM lymph node metastasis, N/A not available, NOS Newcastle–Ottawa Scale, OS overall survival, PFS progression-free survival, RFS recurrence-free survival, SNHG16 small nucleolar RNA host gene 16, TNM tumor node metastasis