Table 2 Stratified analyses of the pooled HRs of overall survival by tumor type, sample size, and survival analysis method
Subgroup analysis | No. of studies | No. of patients | Pooled HR (95% CI) | Heterogeneity | ||
|---|---|---|---|---|---|---|
Fixed model | p-value | I2 (%) | p-value | |||
Survival analysis method | ||||||
 Univariate | 2 | 149 | 1.88 (1.20, 2.96) | 0.006 | 0.0 | 0.472 |
 Multivariate | 4 | 280 | 1.86 (1.51, 2.30) | < 0.001 | 39.9 | 0.173 |
Tumor type | ||||||
 Gynecologic tumor | 2 | 141 | 1.89 (1.24, 2.89) | 0.003 | 0.0 | 0.531 |
 Others | 4 | 288 | 1.86 (1.50, 2.31) | < 0.001 | 41.3 | 0.164 |
Sample size | ||||||
 < 60 | 3 | 132 | 1.72 (1.37, 2.16) | < 0.001 | 0.0 | 0.475 |
 ≥ 60 | 3 | 297 | 2.28 (1.60, 3.24) | < 0.001 | 11.4 | 0.324 |
Cut-off value | ||||||
 Mean | 2 | 149 | 1.88 (1.20, 2.96) | 0.006 | 0.0 | 0.472 |
 Median | 4 | 280 | 1.86 (1.51, 2.30) | < 0.001 | 39.9 | 0.173 |