Fig. 4

Data mining of RAD51, XRCC6 and CFL1. a RSEM of RAD51, XRCC6 and CFL1 in HCC tissues and normal tissues in the TCGA database. Higher expression of RAD51, XRCC6 and CFL1 was observed in HCC tissues ***P ≤ 0.001). b ROC curves of RAD52, RAD51, XRCC6, CFL1, and combined models in diagnosing HCC. Each AUC of the combined model was larger than that of RAD52. The AUC of the combined model (RAD52 and RAD51) was largest in all models (0.924). In each picture, the red solid ROC curve represented the combined model of RAD52 and another protein (the green solid). The blue solid ROC curve represents RAD52. The gray solid represents the reference line. c mRNA expression of RAD51, XRCC6, and CFL1 was confirmed in HCC tissues and adjacent tissues. Upregulated mRNA levels of RAD51, XRCC6, and CFL1 were observed in HCC tissues (*P ≤ 0.05)