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Fig. 4 | Cancer Cell International

Fig. 4

From: TRIM27 promotes the development of esophagus cancer via regulating PTEN/AKT signaling pathway

Fig. 4

The inhibitor LY294002 and 3-BrPA inhibited the effect of TRIM27 in ESCC cells. a The cell proliferation rate detected at 12 h, 24 h and 48 h examined in different cells as indicated. *p < 0.05 vs oeNC, ***p < 0.001 vs oeNC. b Cell apoptosis profile was suppressed in oeTRIM27 transfected cells. **p < 0.01 vs oeNC, ***p < 0.001 vs oeNC; ###p < 0.001 vs oeTRIM27. c The level of 2-NBDG was upregulated in oeTRIM27 transfected cells. *p < 0.05 vs oeNC, ***p < 0.001 vs oeNC; ###p < 0.001 vs oeTRIM27. d The protein level of GLUT1, HKII, cleaved caspase-3, AKT and p-AKT examined in different cells as indicated, ***p < 0.001 vs oeNC; ###p < 0.001 vs oeTRIM27

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