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Fig. 7 | Cancer Cell International

Fig. 7

From: RETRACTED ARTICLE: Silencing of TRIM11 suppresses the tumorigenicity of chordoma cells through improving the activity of PHLPP1/AKT

Fig. 7

Knockdown of TRIM11 reduced the tumorigenicity of chordoma cells in vivo. a, b The tumor volume and weight of siTRIM11 group were significant downregulated compared with that of siNC group. **p < 0.01 vs siNC, ***p < 0.001 vs siNC. c The chordoma cells of siNC tumor were much higher than that of siTRIM11 tumor; Magnification: ×200. d TUNEL staining assay was performed to examine the apoptosis rate of siNC or siTRIM11 tumor, ***p < 0.001 vs siNC; magnification: ×200. e Western blot was used to quantify the protein content of TRIM11 and PHLPP1 in different tumors as indicated. ***p < 0.001 vs siNC

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Cancer Cell International

ISSN: 1475-2867

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