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Fig. 4 | Cancer Cell International

Fig. 4

From: The lncRNA DLX6-AS1 promoted cell proliferation, invasion, migration and epithelial-to-mesenchymal transition in bladder cancer via modulating Wnt/β-catenin signaling pathway

Fig. 4

Overexpression of DLX6-AS1 enhanced Wnt/β-catenin signaling in J82 cells. a Analysis of β-catenin, GSK-3β, c-myc and cyclin D1 mRNA expression by qRT-PCR in J82 cells after being transfected with control vector or DLX6-AS1 overexpressing vector. b Analysis of β-catenin, GSK-3β, c-myc and cyclin D1 protein expression by western blot in J82 cells after being transfected with control vector or DLX6-AS1 overexpressing vector. c Analysis of cell growth by colony formation assay, d analysis of cell proliferation by CCK-8 assay, e analysis of cell invasion by transwell invasion assay, f analysis of cell migration by transwell migration assay, g and h analysis of E-cadherin, vimentin and N-cadherin expression by qRT-PCR and western blot assays in vehicle or XAV939-treated J82 cells after being transfected with control vector or DLX6-AS1 overexpressing vector. N = 3; significant differences between different groups were shown as *P < 0.05, **P < 0.01 and ***P < 0.001

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