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Table 4 Prognostic indicators of pro-B-ALL

From: Clinical-biological characteristics and treatment outcomes of pediatric pro-B ALL patients enrolled in BCH-2003 and CCLG-2008 protocol: a study of 121 Chinese children

Clinico-biological featuresEvent-free survivalMultivariate analysis
Survival rate (%)PHR [95% CI]P
Age (years)
 < 154.5 ± 15.00.0420.534
 ≥ 1087.0 ± 7.0
 1–1074.5 ± 5.0
CD20
 Positive42.9 ± 18.70.0340.087
 Negative78.9 ± 4.2
KMT2A-rearranged
 Positive56.9 ± 9.10.0134.142 [1.535, 11.715]0.005
 Negative81.8 ± 4.3Reference
MRD at day 33
 ≥ 1%34.9 ± 13.2<0.0010.376
 0.01–1%82.8 ± 5.7
 < 0.01%84.6 ± 7.1
MRD at day 78
 ≥ 0.1%36.9 ± 13.8<0.0019.424 [3.210, 27.662]<0.001
 < 0.1%85.0 ± 4.2Reference
  1. Italic signifies P < 0.05