Skip to main content


Fig. 2 | Cancer Cell International

Fig. 2

From: Roles of sphingosine-1-phosphate signaling in cancer

Fig. 2

S1P receptor signaling. S1P exported to the extracellular space binds to the receptors and activates the receptor-bound G-proteins (Gi, Gq, G12/13). The activated G-proteins subsequently trigger the downstream pathways, which plays a role in growth, proliferation, migration and invasion of cancer

Back to article page