Table 2 Subgroup analysis of the relationship between PLR and OS, PFS, DFS, and CSS in UC

OS

 All

9

Random

1.23 (0.95–1.59)

0.124

70.7

0.001

Sample size

 ≤200

6

Random

1.37 (0.87–2.15)

0.174

78.7

<0.001

 >200

3

Tumor type

 UTUC

3

Random

1.47 (0.70–3.12)

0.309

80.2

0.006

 BC

6

Fixed

1.002 (1.000–1.004)

0.049

36.1

0.166

Treatment

 RC

4

Random

1.27 (0.83–1.95)

0.266

56.8

0.074

 RNU

2

Fixed

2.13 (1.48–3.07)

<0.001

47.6

0.167

 TURB

2

Fixed

0.95 (0.74–1.22)

0.666

0

0.409

 NUx

1

–

0.66 (0.32–1.35)

0.253

–

–

PFS

 All

7

Random

1.81 (1.28–2.56)

0.001

60.1

0.020

Sample size

 ≤200

4

Random

1.92 (1.14–3.26)

0.015

58

0.067

 >200

3

Random

1.68 (1.03–2.75)

0.040

60.1

0.020

Tumor type

 UTUC

6

Random

1.67 (1.2–2.31)

0.002

54.8

0.050

 BC

1

–

4.09 (1.52–11.03)

0.005

–

–

DFS

 All

6

Fixed

1.69 (1.31–2.16)

<0.001

0.6

0.412

Sample size

 ≤200

3

Fixed

1.35 (0.94–1.95)

0.103

0

0.573

 >200

3

Fixed

2.05 (1.45–2.90)

<0.001

0

0.535

Tumor type

 UTUC

5

Fixed

1.54 (1.17–2.02)

0.002

0

0.672

 BC

1

–

2.74 (1.46–5.14)

0.002

–

–

Treatment

 RNU

4

Fixed

1.54 (1.17–2.04)

0.002

0

0.504

 TURB

1

–

2.74 (1.46–5.14)

0.002

–

–

 NUx

1

–

1.50 (0.47–4.80)

0.499

–

–

CSS

 All

5

Fixed

1.000 (0.998–1.002)

0.919

0

0.859

Sample size

 ≤200

2

Fixed

1.000 (0.998–1.002)

0.923

0

0.635

 >200

3

Fixed

1.23 (0.82–1.85)

0.311

0

0.968

Tumor type

 UTUC

1

–

1.20 (0.37–3.86)

0.757

–

–

 BC

4

Fixed

1.000 (0.998–1.002)

0.919

0

0.748

Treatment

 RC

2

Fixed

1.000 (0.998–1.002)

0.923

0

0.635

 TURB

2

Fixed

1.24 (0.80–1.91)

0.334

0

0.801

 NUx

1

–

1.20 (0.37–3.86)

0.757

–

–