Fig. 5

Validation of the predictive model. a Kaplan–Meier analysis of OS and PFS for the predictive model in 210 LUAD patients. b The predictive ability of the predictive model compared with single markers and other clinical prognostic parameters by ROC for OS and PFS. c The AUC with the 95% CI for OS and PFS (*P < 0.05). The details for the AUC and 95% CI are also shown in Additional file 2: Table S5. CTHRC1, collagen triple helix repeat containing 1; VEGF, vascular endothelial growth factor; MVD, microvessel density; OS, overall survival; PFS, progression-free survival; LUAD, lung adenocarcinoma; ROC, receiver operating characteristic; AUC, area under the curve