Skip to main content

Table 2 Univariate analysis of factors associated with overall survival and progression-free survival in LUAD patients

From: High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients

VariablesOSPFS
Hazard ratio95% CIP-valueHazard ratio95% CIP-value
Gender1.0670.742–1.5340.7271.0900.759–1.5660.640
Age1.0501.032–1.069<0.0011.5040.993–2.2780.054
Smoking0.9900.637–1.5410.9660.9810.631–1.5250.931
Tumor differentiation0.7240.450–1.1660.1840.8970.574–1.4000.631
Clinical stage2.5722.112–3.132<0.0012.4812.034–3.025<0.001
T classification1.4141.106–1.8080.0061.1630.900–1.5040.248
N classification1.9351.608–2.330<0.0011.7931.480–2.172<0.001
M classification7.1653.673–13.976<0.0016.8733.432–13.766<0.001
CTHRC1 expression2.3001.600–3.308<0.0012.6431.827–3.822<0.001
VEGF expression2.7331.860–4.017<0.0013.6732.485–5.429<0.001
MVD count2.1221.476–3.050<0.0011.8811.305–2.7110.001
  1. CI confidence interval; statistical significance (P < 0.05) is shown in italic
  2. LUAD lung adenocarcinoma, OS overall survival, PFS progression-free survival, CTHRC1 collagen triple helix repeat containing 1, VEGF vascular endothelial growth factor; MVD microvessel density, TNM tumor-node-metastasis