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Table 2 Univariate analysis of factors associated with overall survival and progression-free survival in LUAD patients

From: High CTHRC1 expression may be closely associated with angiogenesis and indicates poor prognosis in lung adenocarcinoma patients

Variables

OS

PFS

Hazard ratio

95% CI

P-value

Hazard ratio

95% CI

P-value

Gender

1.067

0.742–1.534

0.727

1.090

0.759–1.566

0.640

Age

1.050

1.032–1.069

< 0.001

1.504

0.993–2.278

0.054

Smoking

0.990

0.637–1.541

0.966

0.981

0.631–1.525

0.931

Tumor differentiation

0.724

0.450–1.166

0.184

0.897

0.574–1.400

0.631

Clinical stage

2.572

2.112–3.132

< 0.001

2.481

2.034–3.025

< 0.001

T classification

1.414

1.106–1.808

0.006

1.163

0.900–1.504

0.248

N classification

1.935

1.608–2.330

< 0.001

1.793

1.480–2.172

< 0.001

M classification

7.165

3.673–13.976

< 0.001

6.873

3.432–13.766

< 0.001

CTHRC1 expression

2.300

1.600–3.308

< 0.001

2.643

1.827–3.822

< 0.001

VEGF expression

2.733

1.860–4.017

< 0.001

3.673

2.485–5.429

< 0.001

MVD count

2.122

1.476–3.050

< 0.001

1.881

1.305–2.711

0.001

  1. CI confidence interval; statistical significance (P < 0.05) is shown in italic
  2. LUAD lung adenocarcinoma, OS overall survival, PFS progression-free survival, CTHRC1 collagen triple helix repeat containing 1, VEGF vascular endothelial growth factor; MVD microvessel density, TNM tumor-node-metastasis
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Cancer Cell International

ISSN: 1475-2867

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