Fig. 4

Knockdown of ENO1 could partly reverse hyperglycemia-induced EMT in AGS and MGC803 cells. a–c The relationship between the expression of ENO1 and EMT-related transcription factors (Snail, Slug and Twist) was examined by correlation analysis based on GSE84437. d–f The relationship between the expression of ENO1 and EMT-related transcription factors (Snail, Slug and Twist) was examined by correlation analysis based on TCGA database. g Western blot analysis was performed to measure the expression of EMT-related markers under different glucose concentrations. h The effect of ENO1 knockdown on EMT-related marker expression was shown by Western blot. *P < 0.05, **P < 0.01