Table 1 Patient characteristics and 1-, 3-, and 5-year CSS and OS rates
Characteristics | N | % | CSS | OS | ||||
|---|---|---|---|---|---|---|---|---|
1-year (%) | 3-year (%) | 5-year (%) | 1-year (%) | 3-year (%) | 5-year (%) | |||
Gender | ||||||||
Female | 17,427 | 50.6 | 94.5 | 87.1 | 82.3 | 91.7 | 81.0 | 72.6 |
Male | 17,005 | 49.4 | 95.5 | 88.5 | 83.1 | 92.0 | 81.4 | 72.0 |
Race | ||||||||
White | 26,839 | 78.0 | 94.9 | 88.1 | 83.5 | 91.6 | 81.2 | 72.6 |
Othera | 7593 | 22.0 | 95.0 | 87.1 | 82.4 | 92.1 | 81.4 | 71.9 |
Year of diagnosis | ||||||||
2010–2012 | 16,262 | 47.2 | 94.8 | 87.5 | 82.6 | 91.6 | 80.8 | 72.0 |
2013–2015 | 18,170 | 52.8 | 95.2 | 87.9 | 84.5 | 92.0 | 81.6 | 76.8 |
Age at diagnosis | ||||||||
< 60 | 10,602 | 30.8 | 98.3 | 92.8 | 87.7 | 97.6 | 91.1 | 85.0 |
≥ 60 | 23,830 | 69.2 | 93.5 | 85.5 | 80.5 | 89.2 | 76.9 | 66.8 |
Tumor site | ||||||||
Right | 19,807 | 57.5 | 94.3 | 86.5 | 82.0 | 90.8 | 78.9 | 69.9 |
Left | 14,625 | 42.5 | 95.9 | 89.5 | 83.8 | 93.2 | 84.3 | 75.6 |
Histological subtype | ||||||||
AD | 31,239 | 90.7 | 95.2 | 88.3 | 83.3 | 92.1 | 81.9 | 73.0 |
MAD | 2903 | 8.4 | 94.2 | 84.8 | 80.0 | 90.4 | 76.6 | 68.0 |
SRCC | 290 | 0.9 | 78.2 | 58.5 | 51.9 | 74.4 | 52.7 | 44.8 |
Pathologic grade | ||||||||
Grade I | 2585 | 7.5 | 97.1 | 92.3 | 89.0 | 94.3 | 85.9 | 78.3 |
Grade II | 25,438 | 73.9 | 96.0 | 89.6 | 84.6 | 92.9 | 83.1 | 74.2 |
Grade III | 5374 | 15.6 | 90.5 | 79.4 | 73.7 | 87.1 | 72.9 | 63.3 |
Grade IV | 1035 | 3.0 | 87.7 | 74.1 | 68.3 | 84.0 | 67.4 | 58.3 |
T stage | ||||||||
T1 | 3295 | 9.6 | 99.0 | 97.8 | 96.5 | 96.5 | 92.3 | 86.6 |
T2 | 5901 | 17.1 | 97.8 | 96.0 | 93.6 | 94.8 | 88.7 | 81.2 |
T3 | 20,390 | 59.2 | 95.5 | 88.1 | 82.9 | 92.3 | 81.4 | 72.4 |
T4a | 3122 | 9.1 | 88.4 | 70.7 | 60.0 | 84.4 | 64.6 | 51.4 |
T4b | 1724 | 5.0 | 84.0 | 66.6 | 56.7 | 80.7 | 61.4 | 50.8 |
N stage | ||||||||
N0 | 20,991 | 61.0 | 96.9 | 93.2 | 90.1 | 93.7 | 85.9 | 78.0 |
N1 | 9124 | 26.5 | 93.9 | 83.8 | 76.8 | 90.8 | 78.2 | 68.1 |
N2 | 4317 | 12.5 | 87.8 | 69.7 | 59.6 | 84.9 | 64.7 | 53.4 |
Chemotherapy | ||||||||
No | 23,106 | 67.1 | 94.0 | 88.2 | 84.5 | 89.8 | 79.6 | 70.9 |
Yes | 11,326 | 32.9 | 97.0 | 87.0 | 79.5 | 96.0 | 84.3 | 75.2 |
LNH | ||||||||
< 12 | 3562 | 10.3 | 91.9 | 82.6 | 77.3 | 87.2 | 73.8 | 64.1 |
≥ 12 | 30,870 | 89.7 | 95.3 | 88.4 | 83.4 | 92.3 | 82.1 | 73.3 |
LODDS stage | ||||||||
LODDS 1 | 21,981 | 63.8 | 96.9 | 92.9 | 89.7 | 93.6 | 85.6 | 77.7 |
LODDS 2 | 11,376 | 33.0 | 93.1 | 81.4 | 73.4 | 90.2 | 76.0 | 65.3 |
LODDS 3 | 1009 | 2.9 | 78.9 | 54.2 | 44.7 | 75.5 | 49.0 | 39.3 |
LODDS 4 | 66 | 0.3 | 46.1 | 16.8 | 12.0 | 43.2 | 15.8 | 11.3 |
Tumor size | ||||||||
< 4 | 13,757 | 40.0 | 96.9 | 91.6 | 87.4 | 94.0 | 85.2 | 76.6 |
≥ 4 | 20,675 | 60.0 | 93.7 | 85.2 | 79.6 | 90.3 | 78.5 | 69.4 |
CEA | ||||||||
Negative | 22,289 | 64.7 | 96.6 | 91.4 | 87.5 | 94.0 | 85.7 | 77.9 |
Positive | 12,143 | 35.3 | 92.0 | 80.9 | 73.7 | 87.8 | 73.0 | 62.0 |
Tumor deposit | ||||||||
Negative | 32,106 | 93.2 | 95.3 | 88.8 | 84.0 | 92.2 | 82.1 | 73.3 |
Positive | 2326 | 6.8 | 90.3 | 72.8 | 63.2 | 86.8 | 68.1 | 56.6 |
Marriage status | ||||||||
Married | 19,319 | 56.1 | 96.4 | 90.4 | 85.7 | 94.0 | 85.4 | 77.8 |
Single | 5576 | 16.2 | 95.2 | 86.4 | 80.8 | 92.1 | 79.9 | 70.8 |
Separated/Divorced | 3769 | 10.9 | 95.0 | 87.1 | 81.5 | 92.0 | 80.9 | 71.7 |
Widowed | 5768 | 16.8 | 89.9 | 80.3 | 75.2 | 84.2 | 68.7 | 56.2 |
TNM stage | ||||||||
I | 7554 | 21.9 | 98.4 | 97.3 | 95.6 | 95.6 | 90.3 | 83.6 |
II | 13,437 | 39.0 | 96.1 | 90.9 | 87.0 | 92.6 | 83.5 | 74.9 |
III | 13,441 | 39.1 | 92.0 | 79.3 | 71.3 | 88.9 | 73.9 | 63.4 |