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Fig. 2 | Cancer Cell International

Fig. 2

From: miR-149 inhibits cell proliferation and enhances chemosensitivity by targeting CDC42 and BCL2 in neuroblastoma

Fig. 2

Overexpression of miR-149 inhibited cell proliferation, colony formation and promoted apoptosis in NB cells. a, b The expression of miR-149 was measured in SK-N-BE(2)C and SK-N-SH cells transfected with miR-149 or miR-NC by qRT-PCR. c, d Cell proliferation was detected in SK-N-BE(2)C and SK-N-SH cells transfected with miR-149 or miR-NC at different time points by MTT. e, f The numbers of colonies were analyzed in SK-N-BE(2)C and SK-N-SH cells transfected with miR-149 or miR-NC by colony formation assay. g, h Cell apoptosis was examined in SK-N-BE(2)C and SK-N-SH cells transfected with miR-149 or miR-NC by flow cytometry. *P < 0.05, **P < 0.01, compared with miR-NC group

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