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Table 3 Correlation analysis between the lncRNA GAS5 expression and the clinicopathological features of melanoma patients

From: Long non-coding RNA GAS5 accelerates oxidative stress in melanoma cells by rescuing EZH2-mediated CDKN1C downregulation

Clinicopathological featuresCases (n = 75)Expression of lncRNA GAS5p value
Low expression (n = 58, 77.33%)High expression (n = 17, 22.67%)
Gender
 Male2821 (75)7 (25)0.710
 Female4737 (78.72)10 (21.28)
Age
 ≤ 65 years4937 (75.51)12 (24.49)0.373
 > 65 years2621 (80.77)5 (19.23)
Breslow thickness
 ≤ 4 mm186 (33.33)12 (66.67)0.001
 > 4 mm5752 (91.23)5 (8.77)
Ulceration
 No227 (31.92)15 (68.18)0.001
 Yes5351 (96.23)2 (3.77)
Lymph node metastasis
 Negative2412 (42.86)16 (57.14)0.001
 Positive5145 (97.83)1 (2.17)
TNM staging
 I194 (21.05)15 (78.95)0.0001
 II/III5654 (96.43)2 (3.57)
  1. Data were measurement data, expressed by mean ± standard deviation. Data comparison was analyzed by Chi square test. p < 0.05 indicates significant difference