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Table 1 Univariate analyses for prognostic variables of overall survival and disease free survival in colorectal cancer patients using Cox proportional-hazards regression

From: Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway

Characteristic

Overall survival

Disease-free survival

HR

95% CI

P

HR

95% CI

P

Age (years)

  

0.388

  

0.889

≦ 60

1.0

  

1.0

  

 > 60

1.221

0.776–1.921

 

0.967

0.607–1.542

 

T stage

  

< 0.001

  

< 0.001

 1

1.0

  

1.0

  

 2

2.281

0.796–6.537

 

1.404

0.529–3.726

 

 3

3.129

1.078–9.084

 

2.654

1.008–6.988

 

 4

7.692

2.653–22.301

 

5.250

1.980–13.925

 

Lymph node metastasis

  

0.001

  

< 0.001

 Negative

1.0

  

1.0

  

 Positive

2.255

1.415–3.593

 

2.791

1.704–4.570

 

Distant metastasis

  

< 0.001

  

< 0.001

 Negative

1.0

  

1.0

  

 Positive

5.266

2.966–9.351

 

5.111

2.806–9.307

 

TNC

  

0.008

  

0.011

 Negative

1.0

  

1.0

  

 Positive

1.894

1.182–3.035

 

1.893

1.158–3.094