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Table 2 Multivariate analyses for prognostic variables of overall survival and disease free survival in colorectal cancer patients using Cox proportional-hazards regression

From: Tenascin-C predicts poor outcomes for patients with colorectal cancer and drives cancer stemness via Hedgehog signaling pathway

Characteristic

Overall survival

Disease-free survival

HR

95% CI

P-value

HR

95% CI

P-value

Age (years)

  

0.107

  

0.606

≦ 60

1.0

  

1.0

  

 > 60

1.506

0.916–2.477

 

1.141

0.691–1.883

 

T stage

  

0.131

  

0.641

 1

1.0

  

1.0

  

 2

2.461

0.836–7.242

 

1.530

0.553–4.233

 

 3

1.964

0.415–9.286

 

1.204

0.249–5.811

 

 4

3.839

0.682–21.604

 

1.796

0.324–9.942

 

Lymph node metastasis

  

0.419

  

0.187

 Negative

1.0

  

1.0

  

 Positive

1.613

0.506–5.142

 

2.308

0.667–7.987

 

Distant metastasis

  

0.004

  

0.008

 Negative

1.0

  

1.0

  

 Positive

3.307

1.466–7.462

 

3.230

1.365–7.642

 

TNC

  

0.001

  

0.002

 Negative

1.0

  

1.0

  

 Positive

2.192

1.356–3.545

 

2.234

1.353–3.688