Skip to main content

Table 3 Overview of p62-interacting proteins and associated signaling pathways that determine cancer cell fate

From: Insight into the role of p62 in the cisplatin resistant mechanisms of ovarian cancer

Domain

Partner molecules

Signaling

Cell survival/death

References

ZZ

RIP1

NF-κB

Survival

[31]

TB

TRAF6

NF-κB

Survival

[52]

KIR

Keap1

Keap1-Nrf2

Survival

[70]

UBA

Caspase 8

Autophagy

Death

[33, 78]

VDAC

Mitophagy

Survival

[43]

168–224

EGFR

ERFR/Autophagy

Death

[98]