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Table 3 Overview of p62-interacting proteins and associated signaling pathways that determine cancer cell fate

From: Insight into the role of p62 in the cisplatin resistant mechanisms of ovarian cancer

Domain Partner molecules Signaling Cell survival/death References
ZZ RIP1 NF-κB Survival [31]
TB TRAF6 NF-κB Survival [52]
KIR Keap1 Keap1-Nrf2 Survival [70]
UBA Caspase 8 Autophagy Death [33, 78]
VDAC Mitophagy Survival [43]
168–224 EGFR ERFR/Autophagy Death [98]