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Fig. 4 | Cancer Cell International

Fig. 4

From: miR-125a-5p post-transcriptionally suppresses GALNT7 to inhibit proliferation and invasion in cervical cancer cells via the EGFR/PI3K/AKT pathway

Fig. 4

MiR-125a-5p overexpression counteracts the cancer promoting effect induced by GALNT7 in cervical cancer cell lines. HeLa and Caski cells were transfected with NC-mimic, miR-125a-5p mimic, or co-transfected with miR-125a-5p mimic and Vector, miR-125a-5p mimic and pcDNA-GALNT7. The mRNA a, c and protein b, d levels of GALNT7 in HeLa and Caski cells were detected using RT-qPCR and western blot, respectively. e Cell proliferation was measured using the CCK-8 assay after transfection for 24 h. f Cell invasion was detected using the Transwell invasion assay after transfection for 24 h. g Cell apoptosis was measured using Flow cytometry after transfection for 24 h. *P < 0.05, **P < 0.01

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