Skip to main content
Fig. 9 | Cancer Cell International

Fig. 9

From: Silencing of microRNA-135b inhibits invasion, migration, and stemness of CD24+CD44+ pancreatic cancer stem cells through JADE-1-dependent AKT/mTOR pathway

Fig. 9

miR-135b-regulation of JADE-1 inhibited the growth of cancer stem cells and tumors in PC via the AKT/mTOR pathway. miR-135b could promote sphere-forming, cloning, invasion, migration, tumor formation of PCSCs in vivo. The mechanism may be performed through inhibiting JADE-1 and activating AKT/mTOR pathway, thus affecting the stemness of PCSCs and promoting tumor growth

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us