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Fig. 4 | Cancer Cell International

Fig. 4

From: FENDRR suppresses cervical cancer proliferation and invasion by targeting miR-15a/b-5p and regulating TUBA1A expression

Fig. 4

MiR-15a/b-5p restoration or TUBA1A knockdown reverses the effects of FENDRR silencing on CC cell functions. Rescue experiments to test the rescue effects of the rescue group OE/FENDRR + sh-TUBA1A. a, b CCK-8 assay and colony formation assay showed cell viability and proliferation ability change after the overexpression of FENDRR and transfection with rescue group. c Flow cytometry assay proved apoptotic cell number change after overexpressing FENDRR and the treatment of rescue group. d Transwell assay demonstrated effects of FENDRR overexpression and transfection with sh-TUBA1A on cell migration and invasion ability. e Western blot detected EMT process change by FENDRR overexpression and treatment of the rescue group. **p < 0.01

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Cancer Cell International

ISSN: 1475-2867

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