Fig. 6

miR-146a inhibitor offset function of MALAT1 in properties of HCC cell lines. HCC cells underwent simultaneous transfection of siMALAT1/siNC and/or miR-146a inhibitor/NC inhibitor for 48 h. a, b Q-PCR analysis measured the levels of MALAT1 and miR-146a expression in each group. c, d MTT assay showed the proliferation rate of HCC cell lines during 24–72 h after different transfections. e, f FC analysis showed the cell number of apoptosis in HepG2 and Huh-7 cells when treated in different ways. Data were shown as mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.001, in comparison with the siNC + NC inhibitor group; ^#P < 0.05, ^##P < 0.01, ^###P < 0.001, in comparison with siMALAT1 + NC inhibitor group