Fig. 4

LnRNAs modules were analyzed by WGCNA. a The volcano map showing the differentially expressed lncRNAs from TCGA and GTEx. Red spots represent up-regulated genes, and blue spots represent down-regulated genes. b Cluster dendrogram of the co-expression network modules was produced based on topological overlap in the lncRNAs. c The relation of lncRNAs in modules between PAAD tissues and normal samples was investigated. d, e The overlapped target mRNAs obtained by overlapping the significantly up-regulated mRNAs, significantly down-regulated mRNAs, WGCNA-green module and the predicted target mRNAs were analyzed. f The heatmap showing the expression of 161 mRNAs in 178 PAAD patients and 328 normal samples