Fig. 2From: Circular RNA circ-MAT2B facilitates glycolysis and growth of gastric cancer through regulating the miR-515-5p/HIF-1α axisKnockdown of circ-MAT2B weakens GC cell proliferation and glycolysis. a The sketch showing two shRNAs targeting the junction sequence of circ-MAT2B. b qRT-PCR analysis verifying the silencing effect of above two shRNAs. (c–e) Colony formation, EdU and CCK-8 assays detecting the proliferation of AGS and MKN45 cells after circ-MAT2B depletion. f The level of glycolysis determined by glucose uptake and lactate production in AGS and MKN45 cells after circ-MAT2B depletion. Scale bar = 20 μm, **p < 0.01, ***p < 0.001Back to article page