Fig. 4
Correlation between expression of FOXC2 and Ang-2 in HCC tissues. a The correlation between FOXC2 and Ang-2 expression levels (R2 = 0.709, p < 0.0001) in terms of bivariate analysis. b The Ang-2 expression was detected through western blot assay on MHCC-97H and Huh-7 cells when FOXC2 was knocked-down and overexpressed; the membrane was probed with antibody to β-actin. c pGL3-FOXC2 was transfected into MHCC-97H cells that had been previously transfected with Ang-2 promoter-WT, Ang-2 promoter-Mut1, or Ang-2 promoter-Mut2 construct. d The activities of three Ang-2 promoters were determined through luciferase assay. The SD was obtained by conducting three experiments independently